منابع مشابه
Integrase illuminated.
The long struggle to develop effective therapies against human immunodeficiency virus (HIV) continues in earn est. New antiretroviral drugs to prevent integration of the viral genome are undergoing clinical trials. However, the drug development has relied on testing for effectiveness with only limited understanding of the structural aspects of HIV integration. To establish successful infection,...
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Neurotransmitter release occurs by exocytosis of synap-tic vesicles triggered by Ca 2 ϩ influx through voltage-gated Ca 2 ϩ channels. It was found many years ago that release shows a steep dependence on extracellular [Ca 2 ϩ ] and increases approximately with the fourth power of [Ca 2 ϩ ] (Dodge and Rahamimoff, 1967). It was proposed that Ca 2 ϩ entering through voltage-gated Ca 2 ϩ channels bi...
متن کاملThe illuminated plant cell.
The past decade has provided biologists with a palette of genetically encoded, multicolored fluorescent proteins. The living plant cell turned into a 'coloring book' and today, nearly every text-book organelle has been highlighted in scintillating fluorescent colors. This review provides a concise listing of the earliest representative fluorescent-protein probes used to highlight various target...
متن کاملNucleokinesis illuminated Benjamin
Cortical neurons in the brain reach their final position through a highly organized migration in either the radial (from ventricular to pial surface) or tangential (parallel to the ventricular surface) direction1. Most radially migrating neurons move along the processes of radial glia cells through a series of sequential steps. They first extend a leading process in the direction of migration, ...
متن کاملIlluminated 3D Scatterplots
In contrast to 2D scatterplots, the existing 3D variants have the advantage of showing one additional data dimension, but suffer from inadequate spatial and shape perception and therefore are not well suited to display structures of the underlying data. We improve shape perception by applying a new illumination technique to the pointcloud representation of 3D scatterplots. Points are classified...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2010
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2010.58